GLP 1s Reduce Heavy Drinking Days in Patients With Obesity, Alcohol Use Disorder AJMC Naltrexone (at standard dose) was developed and approved to help with opioid and alcohol dependence. Low Dose Naltrexone (LDN) is a different use of the same drug, at a completely different dose, for Obesity drugs improve health but may not reduce overall health care costs The glucagonlike peptide1 system is modulated by acute and chronic alcohol exposure: Findings from human laboratory experiments and a postmortem brain study Farokhnia 2022 Addiction Biology Wiley Online Library